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Pfizer: encouraging data in breast cancer

(CercleFinance.com) - Pfizer and Arvinas today announced positive top-line results from a Phase 3 clinical trial evaluating vepdegestrant monotherapy versus fulvestrant in adults with estrogen receptor-positive and human epidermal growth factor receptor 2-negative (ER+/HER2-) advanced or metastatic breast cancer.


The trial demonstrated a statistically and clinically significant improvement in progression-free survival (PFS) compared with fulvestrant.

This data supports vepdegestrant's potential to give patients whose tumors harbor ESR1 mutations additional time without disease progression, compared with fulvestrant, Pfizer summarizes.


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