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J&J: positive data on nipocalimab

(CercleFinance.com) - Johnson & Johnson announces the publication of data on the differentiated molecular properties of nipocalimab, a monoclonal antibody targeting the neonatal Fc receptor (FcRn).


These preclinical studies show that nipocalimab binds specifically and with high affinity to FcRn, resulting in a reduction of over 75% in circulating IgG (immunoglobulin G) without affecting its production or other immune functions.

These features could make it a therapeutic option for IgG autoantibody diseases such as generalized myasthenia gravis.


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