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GSK: positive phase III data in COPD

(CercleFinance.com) - On Friday, GSK published new positive Phase III data for Nucala in the treatment of chronic obstructive pulmonary disease (COPD), a chronic inflammatory disease.


The trial, involving 806 patients followed for one to two years, met its primary endpoint by showing a 'statistically and clinically significant' reduction in disease-related exacerbations compared to placebo.

Chronic obstructive pulmonary disease (COPD) is an obstruction of the airways caused by an inflammatory response to inhaled toxic substances, often cigarette smoke.

Nucala, a monoclonal antibody, blocks a specific protein called interleukin-5 (IL-5), thereby reducing the overproduction of eosinophils, a type of white blood cell, in the lungs.

The drug is already approved in many markets as an adjunctive therapy for the maintenance treatment of severe asthma.


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